Center for Data Driven Discovery in Biomedicine
Poonam Sonawane is a Scientist responsible for identifying and characterizing underlying molecular and genetic factors and analyzing potential therapeutic targets in pediatric brain tumors. Her research focuses on the effect of neurofibromin loss along with other fusion mutations in NF1-associated optic glioma patients.
Prior to joining CHOP in September 2016, Poonam was a postdoctoral fellow at the Wake Forest School of Medicine. During her postdoctoral research working in Dr. Waldemar Debinski’s lab, Poonam gained experience in immuno-oncology, design, development and characterization of antibody-drug conjugates (ADC’s)/ immunotherapy for glioblastoma (GBM).
Poonam completed a PhD in Cancer Biology from Texas Tech University Health Sciences Center. Her research focused on preclinical-combination drug testing, pharmacogenomics, drug metabolism and PK/PD studies in neuroblastoma patients treated with Isotretinoin (13-cis retinoic acid).