Center for Data Driven Discovery in Biomedicine

Founded in 2016 by Children’s Hospital of Philadelphia’s Chief of Neurosurgery, Dr. Phillip “Jay” Storm,  Alexander B. Wheeler Endowed Chair in Neurosurgical Research, Dr. Adam C. Resnick,  and Executive Director of Research Operations and Strategic Planning, Jena Lilly, the Center for Data Driven Discovery in Biomedicine (D³b) provides personalized care for children through collaborative, data-driven science. 

b’s scientific expertise and diverse research platforms target pediatric cancers and rare diseases of childhood development, with pediatric brain tumors as an area of research emphasis. Its multidisciplinary team unites the fields of basic science, translational research, precision medicine, bioinformatics and genomic research.

Working with collaborators at top-tier research centers around the globe, D³b’s experts have developed cutting edge, cloud-based tools that allow large-scale collection, analysis, and visualization of highly detailed clinical and genomic data drawn from patients across their treatment journey. These tools ensure that researchers everywhere in the world have the resources needed to accelerate the pace of scientific discovery, clinical trial delivery, and improved care for children.   

With these resources available in real-time and accessible anywhere in the world at no cost, tasks that once took researchers and clinicians years to complete can now be completed in months, weeks, or even minutes. 

The D³b Center and its partners are removing previous barriers to research within the Department of Surgery at CHOP, across the CHOP Research Institute, and throughout the entire scientific community. By breaking down silos, D³b is empowering and facilitating researchers everywhere to accelerate translational impact from the bench to the bedside.

b is actively leading childhood (and adult) brain tumor and rare disease research throughout the Philadelphia region and around the globe through partnered efforts such as the Children’s Brain Tumor Network, Philadelphia Coalition for a Cure, and the NIH Common Fund-supported Gabriella Miller Kids First Data Resource Center. 

b receives institutional, philanthropic, and sponsored support to cover the activities  of gathering biospecimens and data; to be shared, at no cost, with researchers worldwide. Together, clinicians, laboratory researchers, data scientists, patient families, and research supporters are working to provide breakthroughs for every child, every time, everywhere.


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Breakthroughs for every child, every time, everywhere.



The mission of The Center for Data Driven Discovery in Biomedicine is to build a transformative healthcare discovery ecosystem providing innovative care for all children through collaborative, data driven science.