Publications

Date Title Author Journal
7/19/2018 Purification of mRNA encoding chimeric antigen receptor is critical for generation of robust T cell response Foster, J. B., Choudhari, N., Perezzelli, J., Storm, J., Hofmann, T. J., Jain, P., ... & Grupp, S. A. Human gene therapy Details
3/16/2018 Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation Jain, Payal, Lea F. Surrey, Joshua Straka, Minjie Luo, Fumin Lin, Brian Harding, Adam C. Resnick, Phillip B. Storm, Anna Maria Buccoliero, Mariarita Santi, Marilyn M. Li, and Angela J. Waanders. Acta Neuropathologica Details
3/5/2018 The landscape of genomic alterations across childhood cancer Gröbner, Susanne N., Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vasilisa A. Rudneva, Pascal D. Johann, Gnana Prakash Balasubramanian, Maia Segura-Wang, Sebastian Brabetz, Sebastian Bender, Barbara Hutter, Dominik Sturm, Elke Pfaff, Daniel Hübschmann, Gideon Zipprich, Michael Heinold, Jürgen Eils, Christian Lawerenz, Serap Erkek, Sander Lambo, Sebastian Waszak, Claudia Blattmann, Arndt Borkhardt, Michaela Kuhlen, Angelika Eggert, Simone Fulda, Manfred Gessler, Jenny Wegert, Roland Kappler, Daniel Baumhoer, Stefan Burdach, Renate Kirschner-Schwabe, Udo Kontny, Andreas E. Kulozik, Dietmar Lohmann, Simone Hettmer, Cornelia Eckert, Stefan Bielack, Michaela Nathrath, Charlotte Niemeyer, Günther H. Richter, Johannes Schulte, Reiner Siebert, Frank Westermann, Jan J. Molenaar, Gilles Vassal, Hendrik Witt, Icgc PedBrain-Seq Project, Icgc Mmml- Seq Project, Birgit Burkhardt, Christian P. Kratz, Olaf Witt, Cornelis M. van Tilburg, Christof M. Kramm, Gudrun Fleischhack, Uta Dirksen, Stefan Rutkowski, Michael Frühwald, Katja von Hoff, Stephan Wolf, Thomas Klingebiel, Ewa Koscielniak, Pablo Landgraf, Jan Koster, Adam C. Resnick, Jinghui Zhang, Yanling Liu, Xin Zhou, Angela J. Waanders, Danny A. Zwijnenburg, Pichai Raman, Benedikt Brors, Ursula D. Weber, Paul A. Northcott, Kristian W. Pajtler, Marcel Kool, Rosario M. Piro, Jan O. Korbel, Matthias Schlesner, Roland Eils, David T. W. Jones, Peter Lichter, Lukas Chavez, Marc Zapatka, and Stefan M. Pfister Nature Details
2/25/2018 Outcomes of Pediatric Craniopharyngioma Resections after Open versus Expanded Endonasal Surgical Approach Douglas, Jennifer E., Bobby A. Tajudeen, Edward C. Kuan, Marvin Bergsneider, Marilene B. Wang, John Y. K. Lee, James N. Palmer, Nithin D. Adappa, and Phillip B. Storm. J Neurol Surg B Details
2/15/2018 The effect and evolution of patient selection on outcomes in endoscopic third ventriculostomy for hydrocephalus: A large-scale review of the literature Madsen, Peter J, Arka N Mallela, Eric D Hudgins, Phillip B Storm, Gregory G Heuer, and Sherman C Stein Journal of the Neurological Sciences Details
2/8/2018 Cerebrospinal Fluid Leak Repaired with Nasoseptal Flap in a 2-Week-Old Neonate Workman, Alan D., Ivy W. Maina, Vasiliki Triantafillou, James N. Palmer, Nithin D. Adappa, Phillip B. Storm, and Jordan T. Glicksman Neurol Surg B, Details
2/2/2018 Posttreatment Rhinosinusitis following Endoscopic Resection of Pediatric Craniopharyngioma Tong, Charles C., Edward C. Kuan, Seerat K. Poonia, Michael A. Kohanski, Justina L. Lambert, Phillip B. Storm, James N. Palmer, and Nithin D. Adappa J Neurol Surg B Details
1/22/2018 Pediatric low-grade gliomas: next biologically driven steps Neuro Oncol Details
1/5/2018 Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects Guha, Manti, Satish Srinivasan, Pichai Raman, Yuefu Jiang, Brett A. Kaufman, Deanne Taylor, Dawei Dong, Rumela Chakrabarti, Martin Picard, Russ P. Carstens, Yuko Kijima, Mike Feldman, and Narayan G. Avadhani Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Details
1/1/2018 Oculoplastic Considerations in Pediatric Craniofacial Surgery Naran, Sanjay, Michael F. Spadola, Phillip B. Storm, and Scott P. Bartlett Pediatric Oculoplastic Surgery Details
11/6/2017 EXTH-58. EFFECTS OF TORC1/2 INHIBITOR MLN0128 ALONE AND IN COMBINATION WITH MEK INHIBITION IN BRAF MUTATED GLIOMA MODELS IN VITRO AND IN VIVO Liu, Kevin X., Sabine Mueller, Rogier Dik, Xiaodong Yang, Steven DuBois, Angela J. Waanders, Adam C. Resnick, William A. Weiss, and Daphne Haas-Kogan Neuro-Oncology Details
11/6/2017 PDTM-40. PEDIATRIC LOW-GRADE GLIOMAS WITH CRAF GENE FUSIONS ARE THERAPEUTICALLY DISTINCT FROM BRAF-FUSIONS BASED ON DIMERIZATION MEDIATED BY N-TERMINAL FUSION PARTNER Jain, Payal, Tamara Fierst, Harry Han, Tiffany Smith, Phillip B. Storm, Angela J. Waanders, and Adam C. Resnick Neuro-Oncology Details
11/1/2017 Developing Cancer Informatics Applications and Tools Using the NCI Genomic Data Commons API Wilson, Shane, Michael Fitzsimons, Martin Ferguson, Allison Heath, Mark Jensen, Josh Miller, Mark W. Murphy, James Porter, Himanso Sahni, Louis Staudt, Yajing Tang, Zhining Wang, Christine Yu, Junjun Zhang, Vincent Ferretti, and Robert L. Grossman Cancer Research Details
10/18/2017 Comprehensive Analysis of Hypermutation in Human Cancer Campbell, BB., Light, N., Fabrizio, D., Zatzman, M., Fuligni, F., de Borja, R., Davidson, S., Edwards, M., Elvin, JA., Hodel, KP., Zahurancik, WJ., Suo, Z., Lipman, T., Wimmer, K., Kratz, CP., Bowers, DC., Laetsch, TW., Dunn, GP., Johanns, TM., Grimmer, MR., Smirnov, IV., Larouche, V., Samuel, D., Bronsema, A., Osborn, M., Stearns, D., Raman, P., Cole, K., Storm, PB., Yalon, M., Opocher, E., Mason, G., Thomas, GA., Sabel, M., George, B., Ziegler, DS., Lindhorst, S., Issai VM., Constantini, S., Toledano, H., Elhasid, R., Farah, R., Dvir, R., Dirks, P., Huang, A., Galati, MA., Chung, J., Ramaswamy, V., Irwin, MS., Aronson, M., Durno, C., Taylor, MD., Rechavi, G., Maris, JM., Bouffet, E., Hawkins, C., Costello, JF., Meyn, MS., Pursell, ZF., Malkin, D., Tabori, U., Shlien, A. PubMed Details
10/12/2017 Novel findings with reassessment of exome data: implications for validation testing and interpretation of genomic data Gibson, Kristin McDonald, Addie Nesbitt, Kajia Cao, Zhenming Yu, Elizabeth Denenberg, Elizabeth DeChene, Qiaoning Guan, Elizabeth Bhoj, Xiangdong Zhou, Bo Zhang, Chao Wu, Holly Dubbs, Alisha Wilkens, Livija Medne, Emma Bedoukian, Peter S. White, Jeffrey Pennington, Minjie Lou, Laura Conlin, Dimitri Monos, Mahdi Sarmady, Eric Marsh, Elaine Zackai, Nancy Spinner, Ian Krantz, Matt Deardorff, and Avni Santani Genetics in Medicine Details
10/9/2017 Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma Alan Mackay, Anna Burford, Diana Carvalho, Elisa Izquierdo, Janat Fazal-Salom, Kathryn R. Taylor, Lynn Bjerke, Matthew Clarke, Mara Vinci, Meera Nandhabalan, Sara Temelso, Sergey Popov, Valeria Molinari, Pichai Raman, Angela J. Waanders, Harry J. Han, Saumya Gupta, Lynley Marshall, Stergios Zacharoulis, Sucheta Vaidya, Henry C. Mandeville, Leslie R. Bridges, Andrew J. Martin, Safa Al-Sarraj, Christopher Chandler, Ho-Keung Ng, Xingang Li, Kun Mu, Saoussen Trabelsi, Dorra H’mida-Ben Brahim, Alexei N. Kisljakov, Dmitry M. Konovalov, Andrew S. Moore, Angel Montero Carcaboso, Mariona Sunol, Carmen de Torres, Ofelia Cruz, Jaume Mora, Ludmila I. Shats, João N. Stavale, Lucas T. Bidinotto, Rui M. Reis, Natacha Entz-Werle, Michael Farrell, Jane Cryan, Darach Crimmins, John Caird, Jane Pears, Michelle Monje, Marie-Anne Debily, David Castel, Jacques Grill, Cynthia Hawkins, Hamid Nikbakht, Nada Jabado, Suzanne J. Baker, Stefan M. Pfister, David T.W. Jones, Maryam Fouladi, André O. von Bueren, Michael Baudis, Adam Resnick, Chris Jones Cancer Cell Details
9/22/2017 GPC2 MAY BE AN IMMUNOTHERAPEUTIC TARGET IN HIGH-RISK NEUROBLASTOMA Bosse, KR, P Raman, Z Zhu, M Lane, D Martinez, and S Heitzeneder. 2017. "GPC2 MAY BE AN IMMUNOTHERAPEUTIC TARGET IN HIGH-RISK NEUROBLASTOMA." In.: AMER ASSOC CANCER RESEARCH 615 CHESTNUT ST, 17TH FLOOR, PHILADELPHIA, PA 19106-4404 USA. AMER ASSOC CANCER RESEARCH Details
9/15/2017 Overcoming Resistance to Single-agent Therapy for Oncogenic BRAF Gene Fusions via Combinatorial Targeting of MAPK and PI3K/mTOR Signaling Pathways Payal Jain, Amanda Silva, Harry J. Han, Shih-Shan Lang, Yuankun Zhu, Katie Boucher, Tiffany E. Smith, Aesha Vakil, Patrick Diviney, Namrata Choudhari, Pichai Raman, Christine M. Busch, Tim Delaney, Xiaodong Yang, Aleksandra K. Olow, Sabine Mueller, Daphne Haas-Kogan, Elizabeth Fox, Phillip B. Storm, Adam C. Resnick and Angela J. Waanders Oncotarget Details
9/11/2017 Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma Kristopher R. Bosse, Pichai Raman, Zhongyu Zhu, Maria Lane, Daniel Martinez, Sabine Heitzeneder, Komal S. Rathi, Nathan M. Kendsersky, Michael Randall, Laura Donovan, Sorana Morrissy, Robyn T. Sussman13, Doncho V. Zhelev, Yang Feng, Yanping Wang, Jennifer Hwang, Gonzalo Lopez, Jo Lynne Harenza, Jun S. Wei, Bruce Pawel, Tricia Bhatti, Mariarita Santi, Arupa Ganguly, Javed Khan, Marco A. Marra, Michael D. Taylor, Dimiter S. Dimitrov, Crystal L. Mackall, John M. Maris Cancer Cell Details
8/14/2017 CRAF Gene Fusions in Pediatric Low-grade Gliomas Define a Distinct Drug Response Based on Dimerization Profiles Jain, P., T. M. Fierst, H. J. Han, T. E. Smith, A. Vakil, P. J. Storm, A. C. Resnick, and A. J. Waanders. Oncogene Details
8/2/2017 Shared ACVR1 Mutations in FOP and DIPG: Opportunities and Challenges in Extending Biological and Clinical Implications Across Rare Diseases Harry J. Han , Payal Jain, Adam C. Resnick, Children's Hospital of Philadelphia Bone Details
7/1/2017 Abstract 4887: Comprehensive molecular analysis of pediatric thalamic tumors Moser, Heloisa H., Susanne Yoon, Madhuri Kambhampati, Sridevi Yadavilli, Angela J. Waanders, Adam Resnick, Roger J. Packer, and Javad Nazarian Cancer Research Details
7/1/2017 Abstract LB-008: The Pediatric Brain Tumor Atlas: building an integrated, multi-platform data-rich ecosystem for collaborative discovery in the cloud Resnick, Adam C., Phillip B. Storm, Angela J. Waanders, Jena V. Lilly, Rishi R. Lulla, Sabine Mueller, Michael Prados, Leonard S. Sender, Allison Heath, Alex S. Felmeister, Anthony Cros, Yuankun Zhu, and Pichai Raman Cancer Research Details
7/1/2017 Abstract 2593: Accelerating pediatric brain tumor research through team science solutions Christini, Amanda, Angela J. Waanders, Joost B. Wagenaar, Alex S. Felmeister, Mariarita Santi, Nitin R. Wadhwani, Jennifer L. Mason, Mateusz P. Koptyra, Jena V. Lilly, Jeffrey W. Pennington, Rishi R. Lulla, and Adam C. Resnick. Cancer Research Details
7/1/2017 Abstract 5614: Novel mRNA purification method with RNaseIII improves efficacy of RNA chimeric antigen receptor T cells Foster, Jessica, Namrata Choudhari, Adam Resnick, and David Barrett Cancer Research Details
7/1/2017 Abstract 2607: The cBioPortal for Cancer Genomics: an open source platform for accessing and interpreting complex cancer genomics data in the era of precision medicine Gao, Jianjiong, Ersin Ciftci, Pichai Raman, Pieter Lukasse, Istemi Bahceci, Adam Abeshouse, Hsiao-Wei Chen, Ino de Bruijn, Benjamin Gross, Zachary Heins, Ritika Kundra, Aaron Lisman, Angelica Ochoa, Robert Sheridan, Onur Sumer, Yichao Sun, Jiaojiao Wang, Manda Wilson, Hongxin Zhang, James Xu, Andy Dufilie, Priti Kumari, James Lindsay, Anthony Cros, Karthik Kalletla, Fedde Schaeffer, Sander Tan, Sjoerd van Hagen, Jorge Reis-Filho, Kees van Bochove, Ugur Dogrusoz, Trevor Pugh, Adam Resnick, Chris Sander, Ethan Cerami, and Nikolaus Schultz Cancer Research Details
7/1/2017 Abstract 3000: Defining the subclonal landscape of high-risk neuroblastoma Harenza, Jo Lynne, Maura A. Diamond, Derek A. Oldridge, Olivia Padovan-Merher, Pichai Raman, Yael P. Mosse, and John M. Maris Cancer Research Details
6/30/2017 The functional variant rs34330 of CDKN1B is associated with risk of neuroblastoma Capasso, Mario, Lee D. McDaniel, Flora Cimmino, Andrea Cirino, Daniela Formicola, Mike R. Russell, Pichai Raman, Kristina A. Cole, and Sharon J. Diskin. Journal of Cellular and Molecular Medicine Details
6/3/2017 Data Commons to Support Pediatric Cancer Research Volchenboum, SL, SM Cox, A Heath, A Resnick, SL Cohn, and R Grossman American Society of Clinical Oncology Details
5/31/2017 Pediatric Low-grade Gliomas with CRAF Gene Fusions are Therapeutically Distinct from Braf-Fusions Based on Dimerization Mediated by N-Terminal Fusion Partner Payal Jain Tamara M. Fierst Harry Han Tiffany Smith Phillip J. Storm Angela J. Waanders Adam C. Resnick Neuro Oncology Details
5/31/2017 GERM-01. GENETIC AND EPIGENETIC LANDSCAPE OF CENTRAL NERVOUS SYSTEM GERM CELL TUMORS Ichimura, Koichi, Yoshiko Nakano, Kai Yamasaki, Mai Kitahara, Kaishi Satomi, Hirokazu Takami, Shintaro Fukushima, Masao Matsutani, and Ryo Nishikawa Neuro-Oncology Details
5/26/2017 Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression Kim, E., Y. Cheng, E. Bolton-Gillespie, X. Cai, C. Ma, A. Tarangelo, L. Le, M. Jambhekar, P. Raman, K. E. Hayer, G. Wertheim, N. A. Speck, W. Tong, and P. Viatour J Exp Med Details
4/4/2017 The Pediatric Brain Tumor Atlas: Building an Integrated, Multi-platform Data-Rich Ecosystem For Collaborative Discovery in the Cloud Adam C. Resnick, Phillip B. Storm, Angela J. Waanders, Jena V. Lilly, Rishi R. Lulla, Sabine Mueller, Michael Prados, Leonard S. Sender, Allison Heath, Alex S. Felmeister, Anthony Cros, Yuankun Zhu, Pichai Raman, Children's Hospital of Philadelphia, UCSF Benioff Children's Hospital, CHOC Children's, Ann & Robert H. Lurie Children's Hospital of Chicago American Association of Cancer Research (AACR) Details
2/20/2017 Transcriptome Analysis of IL-10-stimulated (M2c) Macrophages by Next-generation Sequencing Lurier, E.B., Dalton, D., Dampier, W., Raman, P., Nassiri, S., Ferraro, N.M., Rajagopalan, R., Sarmady, M. and Spiller, K.L. Immunobiology Details
12/20/2016 Enrichment of Targetable Mutations in the Relapsed Neuroblastoma Genome Olivia M. Padovan-Merhar , Pichai Raman , Irina Ostrovnaya, Karthik Kalletla, Kaitlyn R. Rubnitz, Eric M. Sanford, Siraj M. Ali, Vincent A. Miller, Yael P. Mossé, Meaghan P. Granger, Brian Weiss, John M. Maris , Shakeel Modak PLOS Genetics Details
12/14/2016 MYB-QKI Drives Childhood Brain Tumors via Tripartite Mechanism Payal Jain & Adam C. Resnick, Center for Data Driven Discovery in Biomedicine at Children's Hospital of Philadelphia Cell Cycle Details
11/21/2016 PedcBioPortal: A cancer data visualization tool for integrative pediatric cancer analyses Pichai Raman, Alex S Felmeister, Phillip B Storm, Rishi R.Lulla, Angela J Waanders, and Adam C Resnick, on behalf of the complete team membership of the Children’s Brain Tumor Tissue Consortium (CBTTC)., CBTTC THE SOCIETY FOR NEURO-ONCOLOGY Details
11/7/2016 PedcBioPortal: A Cancer Data Visualization Tool for Integrative Pediatric Cancer Analyses Pichai Raman, Adam C Resnick, Phillip B Storm, Sabine Mueller, Nikolaus Schultz, Ethan Cerami, John M Maris, Angela J Waanders. Neuro-Oncology Details
11/1/2016 Inositol Polyphosphates Intersect with Signaling and Metabolic Networks via Two Distinct Mechanisms Wu M, Chong LS, Perlman DH, Resnick AC, Fiedler D Proceedings of the National Academy of Sciences of the United States of America Details
10/31/2016 Cavatica: empowering research with a pediatric genomic cloud Pichai Raman, Alex S Felmeister, Phillip B Storm, Rishi R.Lulla, Angela J Waanders, and Adam C Resnick, on behalf of the complete team membership of the Children’s Brain Tumor Tissue Consortium (CBTTC)., CBTTC CAC2 Details
8/18/2016 The Biorepository Portal Toolkit: An Honest-Brokered, Modular, Service-Oriented Software Tool Set for Biospecimen-driven Translational Research Alex S. Felmeister, Aaron J. Masino, Tyler J. Rivera, Adam C. Resnick and Jeffrey W. Pennington, Children's Hospital of Philadelphia BioMed Central Genomics Details
7/1/2016 Pediatric Low-grade Gliomas with CRAF Fusions Respond Differentially to Targeted Therapeutics Based on their Dimerization Profiles Payal Jain, Tamara Fierst, Amanda Silva, Jake Budlow, Harry Han, Phillip B. Storm, Angela Waanders and Adam Resnick AACR Cancer Research Details
7/1/2016 Pediatric low-grade gliomas with CRAF fusions respond differentially to targeted therapeutics based on their dimerization profiles Payal Jain, Tamara Fierst, Amanda Silva, Jake Budlow, Harry Han, Phillip B. Storm, Angela Waanders, and Adam Resnick American Association for Cancer Research Details
6/18/2016 Development of robust in vitro and in vivo preclinical models for diffuse intrinsic pontine glioma Yadavilli S, Yang X, Kilburn L, Kilburn L, Magge S, Kambhampati M, Waanders A, Han H. Muellar S, Resnick A, Packer R, Nazarian J Neuro-Oncology Details
5/30/2016 ACVR1-Mutant diffuse intrinsic pontine gliomas (DIPGS) acquire abeerant activin-mediated bmp pathway activation Harry Han, Valerie Baubet, Katie Boucher, Robert Pignolo, Frederick Kaplan, Eileen Shore, Phillip Storm, Nadia Dahmane, and Adam Resnick Neuro-Oncology Details
5/30/2016 Precision Medicine Approach for Children with Diffuse Intrinsic Pontine Glioma Mueller S, Liang W, Gupta N, Kuhn J, Kilburn L, Crawford J, Banerjee A, Nazemi K, Packer R, Nazarian J, Petritsch C, Truffaux N, Roos A, Nicolaides T, Waanders A, Resnick A, Craig D, Carpten J, Byron S, Berens M, Prados M Neuro-Oncology Details
2/1/2016 MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism Pratiti Bandopadhayay, Lori A Ramkissoon, Payal Jain, Guillaume Bergthold, Jeremiah Wala, Rhamy Zeid, Steven E Schumacher, Laura Urbanski, Ryan O'Rourke, William J Gibson, Kristine Pelton, Shakti H Ramkissoon, Harry J Han, Yuankun Zhu, Namrata Choudhari, Amanda Silva, Katie Boucher, Rosemary E Henn, Yun Jee Kang, David Knoff, Brenton R Paolella, Adrianne Gladden-Young, Pascale Varlet, Melanie Pages, Peleg M Horowitz, Alexander Federation, Hayley Malkin, Adam A Tracy, Sara Seepo, Matthew Ducar, Paul Van Hummelen, Mariarita Santi, Anna Maria Buccoliero, Mirko Scagnet, Daniel C Bowers, Caterina Giannini, Stephanie Puget, Cynthia Hawkins, Uri Tabori, Almos Klekner, Laszlo Bognar, Peter C Burger, Charles Eberhart, Fausto J Rodriguez, D Ashley Hill, Sabine Mueller, Daphne A Haas-Kogan, Joanna J Phillips, Sandro Santagata, Charles D Stiles, James E Bradner, Nada Jabado, Alon Goren, Jacques Grill, Azra H Ligon, Liliana Goumnerova, Angela J Waanders, Phillip B Storm, Mark W Kieran, Keith L Ligon, Rameen Beroukhim, Adam C Resnick Nature Genetics Details
1/30/2016 A Novel Inositol Pyrophosphate Phosphatase in Saccharomyces cerevisiae: Siw14 Protein selectively cleaves the β- Phosphate from 5-Diphosphoinositol pentakisphosphate (5PP-IP5) Elizabeth A. Steidle, Lucy S. Chong, Mingxuan Wu, Elliot Crooke, Dorothea Fiedler, Adam C. Resnick and Ronda J. Rolfes Journal of Biological Chemistry Details
12/17/2015 Scalable Biobanking: A Modular Electronic Honest Broker and Biorepository for Integrated Clinical, Specimen and Genomic Research Alex S. Felmeister, Tyler J. Rivera, Aaron J. Masino, Adam C. Resnick, Jeffrey W. Pennington, Children's Hospital of Philadelphia 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Details
4/21/2015 Combinatorial pathway targeting approaches for BRAF fusions associated with pediatric low-grade gliomas. Waanders A, Silva A, Chen S-S, Han H, Zhu Y, Boucher K, Jain P, Fierst T, Choudhari N, Mueller S, Haas-Kogan D, Storm P, Resnick A Neuro Oncology Details
4/21/2015 Targeted combinatorial approach for treatment of pediatric low grade gliomas in the context of BRAFV600E and KIAA1549:BRAF mutations. Olow AK, Mueller S, Yang X, Hashizume R, Meyerowitz J, Weiss W, Resnick A, Waanders A, Berger M, Gupta N, James CD, Hass-Kogan D Neuro Oncology Details
4/21/2015 Effects of TORC1/2 inhibitor MLN0128 alone and in combination with MEK inhibition in BRAF mutated glioma cells. Mueller S, Dik R, Yang X, Aleksandra O, Gustafson C, DuBois S, Weiss W, Waanders A, Resnick A, Haas-Kogan D Neuro-Oncology Details
2/3/2014 Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas Brastianos PK, Taylor-Weiner A, Manley PE, Jones RT, Dias-Santagata D, ThornerAR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L, Sunkavalli A, Shillingford N, Calicchio ML, Lidov HG, Taha H, Martinez-Lage M, Santi M, Storm PB, Lee JY, Palmer JN, Adappa ND, Scott RM, Dunn IF, Laws ER Jr, Stewart C, LigonKL, Hoang MP, Van Hummelen P, Hahn WC, Louis DN, Resnick AC, Kieran MW, Getz G, Santagata S. Nature Genetics Details