First-of-its-Kind Open-Analysis Platform for Pediatric Brain Tumors Provides Robust Data Resource for Childhood Cancer Research
– Collaboration among CHOP, Alex’s Lemonade Stand Foundation, the Pacific Pediatric Neuro-Oncology Consortium, and Children’s Brain Tumor Network paves the way for new collaborative models to accelerate discoveries…
Researchers Uncover New Understanding of Medulloblastoma in CBTN Datasets
Almost all of the DNA of the human genome is located on 23 pairs of chromosomes, each a long coil of a single tightly-wound DNA strand. When a…
CHOP-led Pediatric Hospital Network Receives Critical Government Support for Genetic Research of Pediatric Tumors
Project will allow thousands of tissue samples to be studied and provide an enormous level of insight into childhood cancer PHILADELPHIA, November 2, 2021 – Unlocking the genetic mysteries…
ACCELERATE Consortium and Pediatric Brain Tumors Across Appalachia
With its operations center housed at the Center for Data Driven Discovery in Biomedicine (D3b) at Children’s Hospital of Philadelphia (CHOP), Children’s Brain Tumor Network (CBTN) is a…
Latest Research Developments at D³b – Spring 2021
Recently shared with the Children’s Hospital of Philadelphia (CHOP) Research Institute, the Center for Data Driven Discovery in Biomedicine (D3b) has compiled a report on its most significant…
New D3b Research Projects – Spring 2019
Pediatric brain tumor miRNA profiling for the cohort of Children’s Brain Tumor Network specimens D³b’s The Molecular Diagnostics Research Unit (MDRU) will generate the data and lead this…
New D3b Research Collaborations – Spring 2019
Project Genie Project Genomics, Evidence, Neoplasia, Information, Exchange (Project GENIE) is an AACR pilot project that seeks to identify and validate genomic biomarkers relevant to cancer treatment…
#BrainTumorAwarenessMonth: Increased Support of Collaborative Brain Tumor Research is Critical to Improving Treatments and Discovering Cures for Children
*Note: This article comes courtesy of the Children’s Brain Tumor Network (CBTN), for which the Center for Data Drive Discovery in Biomedicine is the operations center. The CBTN…
CHOP-Led Gabriella Miller Kids First Data Resource Center Launches New NIH-Funded Childhood Disease Research Portal
Researchers, clinicians and families now have access to a powerful, open-source and cloud-based data resource to share important information about childhood diseases, including pediatric cancer and birth defects,…
Novel FGFR2-INA fusion identified in two low-grade mixed neuronal-glial tumors drives oncogenesis via MAPK and PI3K/mTOR pathway activation
Jain, Payal, Lea F. Surrey, Joshua Straka, Minjie Luo, Fumin Lin, Brian Harding, Adam C. Resnick, Phillip B. Storm, Anna Maria Buccoliero, Mariarita Santi, Marilyn M. Li, and…