Center for Data Driven Discovery in Biomedicine
Dr. Mateusz Koptyra is a Senior Scientist responsible for initiation, coordination and implementation of scientific projects around the Center’s research units. His team identifies the research demands at the clinical level and creates pipelines for projects to test the research proposals at a pre-clinical level, with a primary focus on quality data generation in genomic, transcriptomic and proteomic tumor profiling for the biomarker search. Mateusz is also responsible for exploration and validation of the platforms to be utilized for Center’s pipelines, and improvements of sample collection, handling and storage methods to empower the Children’s Brain Tumor Tissue Consortium pipeline. His research focuses on non-invasive diagnostics in pediatric brain tumors, biomarker search, cell-free DNA/RNA, and extra-cellular vesicles, including the development of non-invasive medulloblastoma tumor profiling using circulating in blood tumor material (cell-free DNA).
Prior to joining CHOP in September of 2011, Mateusz worked as a research assistant to explore diagnostic utilities for breast cancer at the Center of Oncology in Warsaw, Poland. Additionally, he worked as a research scholar at Temple University where he studied mechanisms for therapy resistance to small molecule inhibitors in chronic myeloid leukemia, before completing a post-doctoral fellowship at Thomas Jefferson University to explore the role of Stat5 transcription factors in prostate cancer models.
Mateusz earned an MS degree from Warsaw University and completed his PhD from the Medical University of Warsaw in Warsaw, Poland. He is committed to empowering non-invasive diagnostics for pediatric brain tumors. He aims to bring a small chunk of meaningful quality research data which will lead to improvement in clinic for any child in need.