Development and Clinical Validation of a Large Fusion Gene Panel for Pediatric Cancers
Abstract Gene fusions are one of the most common genomic alterations in pediatric cancer. Many fusions encode oncogenic drivers and play important roles in cancer diagnosis, risk stratification,…
Sclerosing Epithelioid Fibrosarcoma of the Bone With Rare EWSR1-CREB3L3 Translocation Driving Upregulation of the PI3K/mTOR Signaling Pathway
Abstract Sclerosing epithelioid fibrosarcoma (SEF) is an uncommon neoplasm that rarely presents in bone. It is characterized by epithelioid cells arranged in nests and single-file cords within a…
Immunotherapy for pediatric brain tumors: past and present
Abstract The field of cancer immunotherapy has progressed at an accelerated rate over the past decade. Pediatric brain tumors thus far have presented a formidable challenge for immunotherapy…
Research & Administrative Progress Report
Click HERE to view/download [.pdf file format] the D3b Research & Administrative Progress Report
CHOP’s Center for Data Driven Discovery in Biomedicine Joins the Division of Neurosurgery and Neuro-Oncology Program to Honor Brain Tumor Awareness Month
According to the Central Brain Tumor Registry of the United States (CBTRUS), an estimated 86,970 new cases of primary malignant and non-malignant brain and central nervous system (CNS)…
#BrainTumorAwarenessMonth: Increased Support of Collaborative Brain Tumor Research is Critical to Improving Treatments and Discovering Cures for Children
*Note: This article comes courtesy of the Children’s Brain Tumor Network (CBTN), for which the Center for Data Drive Discovery in Biomedicine is the operations center. The CBTN…
Design Principles
To accelerate translational research and the processing of data using the D³b Methodology, new platforms, research environments, and tools are required, which must be built on the following…
D3b Co-director Jay Storm Receives HealthCare Heroes Award
To read the entire announcement, visit http://www.libertymuseum.org/awards/healthcare-heroes/honorees/ THE NATIONAL LIBERTY MUSEUM CELEBRATES OUTSTANDING PHYSICIANS AND RESEARCHERS AT THE FIRST ANNUAL HEALTHCARE HEROES AWARD ON NOVEMBER 19, 2018 The National…
Meeting of the Minds: Children’s National Hosts First DIPG Round Table Discussion
Over 40 experts involved in the study and treatment of diffuse intrinsic pontine gliomas (DIPG) convened at the inaugural DIPG Round Table Discussion at Children’s National Health System…
Biden Cancer Summit – Center Director Jay Storm to Speak
On Friday, September 21st, Dr. Phillip “Jay” Storm CO-Director of the Center for Data Driven Discovery in Biomedicine joined the Biden Cancer Community Summit in Washington D.C. to…