Cranial fetus In Fetu. Case Illustration
Separation of Craniopagus Twins by a Multidisciplinary Team
Conjoined twins who are classified as craniopagus (joined at the cranium) have a rare congenital anomaly. Despite advances in surgical techniques and critical care, the rate of complications…
Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor
Abstract The authors present the case of en bloc resection of a clival-C2 atypical teratoid/rhabdoid tumor. These aggressive lesions of early childhood generally occur in the cerebellum or…
Surgical Management of Pediatric Brain Tumors
Abstract Brain tumors are the most common cause of cancer-related death and the second most common form of cancer in pediatric patients. Many of these tumors are treated…
Treatment of Pediatric Atlantoaxial Instability with Traditional and Modified Goel-harms Fusion Constructs
Abstract There are several treatment options for rigid fixation at C1–C2 including Brooks and Gallie type wired fusions and C1–2 transarticular screws. The use of a Goel–Harms type…
Cerebral Salt Wasting Syndrome in Post-op-erative Pediatric Brain Tumor Patients
Abstract BACKGROUND: Cerebral salt wasting syndrome (CSWS) and the syndrome of inappropriate antidiuretic hormone (SIADH) are both causes of hyponatremia in pediatric neurosurgical patients often with similar presenting…
Shared ACVR1 mutations in FOP and DIPG: Opportunities and challenges in extending biological and clinical implications across rare diseases
Abstract Gain-of-function mutations in the Type I Bone Morphogenic Protein (BMP) receptor ACVR1 have been identified in two diseases: Fibrodysplasia Ossificans Progressiva (FOP), a rare autosomal dominant disorder…
IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration
Abstract Autophagy plays a broad role in health and disease. Here, we show that inositol polyphosphate multikinase (IPMK) is a prominent physiological determinant of autophagy and is critical…
Anti-N-methyl-D-as-partate Receptor-mediated Encephalitis in Infants and Toddlers: Case Report And Review of the Literature
Abstract BACKGROUND: Anti-N-methyl-D-aspartate receptor encephalitis is an increasingly well-recognized inflammatory encephalitis in children and adults. PATIENT: We report a previously healthy 21-month-old girl who presented with behavioral change,…
Pediatric Nasoseptal Flap Reconstruction for Suprasellar Approaches
Abstract OBJECTIVES/HYPOTHESIS: To determine the pediatric age groups viable for nasoseptal flap (NSF) reconstruction of endoscopic endonasal approaches (EEA) to intracranial pathology of suprasella neoplasms. STUDY DESIGN: Retrospective…